11 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... PURPURA: Vasculitis ... Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... Petechiae, Palpable purpura ... #skin #dermatology ... #rheumatology # ... differential #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Diagnosis: Vasculitis ... • Goodpasture syndrome ... #dermatology #rash ... #diagnosis #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Skin ulcers ... - GPA, EGPA, microscopic ... #types #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis - Skin ... Diagnosis: Systemic ... differential #diagnosis ... #rheumatology # ... classification
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Sarcoidosis • GPA ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #rashes #differential ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... Diagnosis #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... • Neutrophilic dermatosis ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
malignancies, vasculitis ... processes: • Systemic ... necrosis • Purpura ... #rheumatology # ... hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... Vasculitis: • ... 7%, Cryoglobulinemia ... #Rheumatology #