4 results
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Neutrophilic dermatosis ... • Coombs (-) hemolytic ... #Hematology #Monoclonal ... #Differential # ... Diagnosis #Oncology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
DIC/TTP/HUS - Hemolytic ... Pigmented Purpuric Dermatosis ... ANCA associated small ... #Diagnosis #hematology ... #rheumatology #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... - Idiopathic monoclonal ... younger pts) Differential ... the RBCs causing intravascular ... #anemia #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... abnormalities SMALL ... pain, infarct • Small ... #rheumatology # ... classification