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diagnosis cryoglobulins dermatology erythematosus glomerulonephritis monoclonal nonpalpable oncology palpable paraproteinemias purpura rapidly rpgn sle systemic types vasculitides
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... #differential # ... diagnosis #algorithm ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
proteinuria, rapidly progressing ... +MPO) • Cryoglobulinemic ... such as systemic lupus ... #rheumatology # ... classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
DDX: • ANCA (Antineutrophil ... (e.g. systemic lupus ... diagnosis #types #classification ... #rheumatology # ... vasculitis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Pigmented Purpuric Dermatosis ... /HSP • Cryoglobulinemia ... (MIXED) • ANCA ... #Diagnosis #hematology ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... + MPO) Cryoglobulinemic ... - interstitial keratitis ... Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... vein thrombosis Hematologic ... Erythematosus #Diagnosis #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Neutrophilic dermatosis ... (Cryoglobulinemic ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
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