12 results
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
lung disease ... Gastrointestinal inflammatory disease ... Granulomatous disease ... • Liver diseases ... interstitial lung disease
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... weeks without infection ... cells can indicate disease ... #workup #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> AML: Blast crises ... • Tumor lysis syndrome ... Agranulocytosis • Hypogammaglobulinemia ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... Complications: 1) Infection ... due to hypogammaglobulinemia ... to large cell lymphoma ... chemotherapy for low-risk disease
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Venoocclusive disease ... Hereditary: Wilson Disease ... Hemochromatosis, Celiac disease ... of cholestatic disease ... Alcoholic liver disease
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
Chronic infections ... congenital heart disease ... interstitial lung disease ... Seen in liver disease ... #Diagnosis #Clinical
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... - Clinical Presentation ... number of sites of disease ... #diagnosis #classification ... #hematology #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... diseases (i.e. ... (e.g. thyroid disease ... ) • Kikuchi disease ... • Castleman's disease
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Systemic rheumatic diseases ... atherosclerotic disease ... most important diseases ... (GRANULOMATOUS DISEASE ... HBV Kawasaki Disease
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Myeloproliferative Disease ... • Parvovirus infection ... #diagnosis #hematology ... #oncology