5 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
cold agglutin disease ... Mycoplasma pneumoniae infection ... e.g. sickle cell disease ... spherocytosis) • Infections ... diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... SLE) - Viral infections ... APLS • Acute Infectious ... : Schamberg Disease ... #Diagnosis #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung disease ... • Infectious ... Granulomatous disease ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
rheumatic diseases ... to exclude are infections ... Recurrent middle ear infections ... , recent viral infection ... #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Autoimmune disorders ... number of sites of disease ... classification #hematology ... #oncology #management