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diagnosis differential champs cryoglobulins hypocomplementemia low mnemonic monoclonal oncology sle systemic vasculitides
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Mnemonic C - Cryoglobulinemia ... S - Systemic Lupus ... Erythematosus ( ... total 50, renal ... #differential #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Low serum C4 complement ... (e.g. systemic lupus ... erythematosus ( ... #classification ... #rheumatology #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Neutrophilic dermatosis ... (Cryoglobulinemic ... to cold IgG • Lupus ... vascular beds-renal ... #Hematology #Monoclonal
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... Kikuchi disease • Type-I ... APLA/LAC: • Renal ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... erythematosus, ... against MPO • Complement ... differential #diagnosis #rheumatology ... #classification
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