5 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• IgA vasculitis ... • Vasculitis ... #diagnosis #types ... #rheumatology # ... vasculitis
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
S - Systemic Lupus ... Erythematosus ( ... total 50, renal ... #differential # ... hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
• Complement (Low ... Serologies for Cryoglobulins ... differential #diagnosis ... #rheumatology # ... classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
vasculitis, rheumatoid ... • Mesenteric vasculitis ... APLA/LAC: • Renal ... inflammation Cutaneous Vasculitis ... #Diagnosis #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential