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dermatology alopecia hairloss vasculitis antinuclear autoimmune cryoglobulinemia cryoglobulins dermatologic diffuse erythematosus focal gpa granulomatosis hair loss management myopathy myositis polyangiitis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... , Polymyositis/Dermatomyositis ... Lymphoproliferative Disorders, Infection ... #rheumatology #diagnosis ... #differential
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Allopecia - Differential ... Diagnosis Framework ... Capitis - Skin ... Disease: Discoid lupus ... , Loose anagen syndrome
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Diagnosis Algorithm ... planopilaris Pattern ... • Loose anagen syndrome ... #Diagnosis #Algorithm ... #causes
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Disease Classification ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Still disease, dermatomyositis ... fibromyalgia) • Infections
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
causes arthritis ... LFT • ESR • ANA ... ) pattern: antibodies ... #diagnosis #rheumatology ... #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... : • Clinical triad ... (e.g. systemic lupus ... #types #classification ... #rheumatology #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... • Goodpasture syndrome ... with a certain pattern ... #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Tenderness → Consider infectious ... ) • Anti-Mi2 (skin ... pattern of muscle ... statins - probably caused
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... • Inner ear • Skin ... : • Clinical tests ... Anti-Matrilin-1 Ab ○ Antibodies ... Polychondritis #rheumatology
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