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diagnosis anemia hematology hemolytic causes dermatologic dermatology erythematosus extravascular gpa granulomatosis hemolysis polyangiitis sle systemic vasculitides
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... usually IgG) (e.g. lupus ... agglutin disease ... , Copper and lead ... #Causes #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... Agglutinin Disease ... Agglutinin Syndrome ... #agglutinin #disease
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Others: • Lupus ... mucositis - Rash ... to exclude are infections ... #rheumatology # ... classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Classification: ... permanent alopecia Differential ... fibromyalgia) • Infections ... Clinical Features
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... reticularis Differential ... • Goodpasture syndrome ... , extravascular ... #diagnosis #rheumatology
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