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hematology anemia antinuclear causes cold cryoglobulinemia cryoglobulins erythematosus extravascular hemolysis hodgkins intravascular lymphoma management monoclonal paraproteinemias patterns sle systemic types
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
pallor, dyspnea, and ... Diagnosis: • hemolytic ... testing for anti-C3d and ... hemoglobinemia and ... #disease #hemolytic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... . primary cold agglutin ... , Copper and lead ... Extravascular #Causes #differential ... #diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
LFT • ESR • ANA ... ) pattern: antibodies ... differential #diagnosis ... #rheumatology # ... classification
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... SLE), Sjogren's Syndrome ... Lymphoproliferative Disorders, Infection ... #rheumatology #diagnosis ... #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Classification: ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... fibromyalgia) • Infections
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Amyloidosis and ... histiocytosis, and ... to cold IgG • Lupus ... @KirtanPatolia and ... #Diagnosis #Oncology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
temperatures below 37°C and ... endothelial injury and ... : • Clinical triad ... ) • Types II and ... #rheumatology #
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... nodosum • Immune hemolytic ... number of sites of disease ... #hematology #oncology
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