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diagnosis differential causes classification dermatology rheumatology cryoglobulinemia monoclonal oncology paraproteinemias petechiae petechial physicalexam rash types vasculitides vesiculobullous
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Vascular Sludging ... Hyperviscosity Syndrome ... 20% Sjögren's syndrome ... (e.g. systemic lupus ... classification #rheumatology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Differential Diagnosis Algorithm ... • Contact dermatitis ... Bullous systemic lupus ... drug eruption #Vesicular ... Vesiculobullous #SkinRash
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... and bullous or vesicular ... lesions-interstitial keratitis ... such as systemic lupus ... Serologies for Cryoglobulins
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Disruptions in vascular ... Infection - Vasculitis ... (lupus, RA, Sjogren's ... immunoglobulins & cryoglobulins
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Neutrophilic dermatosis ... to cold IgG • Lupus ... Subcorneal pustular dermatosis ... (Thrombosis in vascular ... Paraproteinemias #Hematology
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