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Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
in Systemic Lupus ... #diseases #SLE ... #Systemic #Lupus ... #nephritis #classification ... #types #rheumatology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
during hemolytic disease ... lupus erythematosus ... - Contact dermatitis ... #Types #Classification ... #Diagnosis #Reactions
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Chain deposition disease ... Lupus Erythematosus ... (total 50, renal ... #differential # ... hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Decade Skin Disease ... Classification: ... diseases (i.e. ... #Diagnosis #Rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... • Low serum C4 complement ... lupus erythematosus ... #types #classification ... #rheumatology #
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
(Granulomatous disease ... Diagnosis: Systemic ... rheumatic diseases ... atherosclerotic disease ... #diagnosis #rheumatology