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differential hematology classification agglutinin anemia cold nonpalpable palpable paraproteinemias types vasculitides
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... : - 10% SLE or ... ) • Cutaneous ... (e.g. systemic lupus ... classification #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... Scleromyxedema (CNS ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Diagnosis Framework ... DIC/TTP/HUS - Hemolytic ... Dermatosis: Schamberg ... /HSP • Cryoglobulinemia ... #hematology #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
such as systemic lupus ... strong sign of cutaneous ... , and SLE) • Urinalysis ... Serologies for Cryoglobulins ... #rheumatology #
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Agglutinin Syndrome (CAS ... presentation) • Cutaneous ... Diagnosis: • hemolytic ... #hematology #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... , such as SLE, atherosclerotic ... / ANCA + MPO) Cryoglobulinemic ... chorioretinitis, CNS ... #Rheumatology
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