8 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Gravis, Graves' Disease ... Type III Hypersensitivity ... Lupus Erythematosus ... , Reactive Arthritis ... #Types #Classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
during hemolytic disease ... arthritis, and ... systemic lupus erythematosus ... #Types #Classification ... #Reactions #Table
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... , rheumatoid arthritis ... diseases (i.e. ... #Systemic #Lupus ... #Diagnosis #Rheumatology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
to complement activation ... , Haemolytic disease ... days - Examples: Rheumatoid ... lupus erythematosus ... #reactions #types
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... lupus erythematosus ... (SLE), rheumatoid ... #types #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
(Granulomatous disease ... : Systemic rheumatic ... diseases, such ... as systemic lupus ... atherosclerotic disease
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... • Systemic lupus ... • Kawasaki disease ... of underlying disease ... lupus erythematosus
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
: • Systemic rheumatic ... diseases, such ... disease, drug reactions ... most important diseases ... (GRANULOMATOUS DISEASE