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allergy differential table vasculitis comparison hematology management activation allergic champs cryoglobulinemia cryoglobulins definitions druginduced hypocomplementemia laboratory macrophage mas pathophysiology rheumatic
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Gravis, Graves' Disease ... Type III Hypersensitivity ... Lupus Erythematosus ... , Reactive Arthritis ... #Types #Classification
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
during hemolytic disease ... , and systemic lupus ... erythematosus ... #Types #Classification ... #Reactions #Table
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
, Haemolytic disease ... glomerulonephritis, Systemic ... lupus erythematosus ... Examples: Contact dermatitis ... #reactions #types
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Decade Skin Disease ... diseases (i.e. ... #Systemic #Lupus ... #Diagnosis #Rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Chain deposition disease ... Lupus Erythematosus ... Hypocomplementemia #Low ... #Complement #CHAMPS ... #Mnemonic #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... factor level • Low ... lupus erythematosus ... #types #classification ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... Lupus Erythematosus ... Evolution: Chronic disease ... #table #rheumatology ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
(Granulomatous disease ... diseases, such ... as systemic lupus ... atherosclerotic disease ... most important diseases
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
highly inflammatory disease ... • Systemic lupus ... • Kawasaki disease ... of underlying disease ... lupus erythematosus
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Studies in Rheumatic Diseases ... lupus erythematosus ... exclude inflammatory disease ... connective-tissue disease ... #Rheumatic #Disease
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