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differential hypersensitivity ana antinuclear table vasculitis allergic comparison cryoglobulinemia cryoglobulins definitions laboratory pathophysiology rheumatic rheumatoid vasculitides workup
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Gravis, Graves' Disease ... Lupus Erythematosus ... , Reactive Arthritis ... #Allergic #Reactions ... #Types #Classification
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... (SLE), Systemic ... #rheumatology #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... : Lupus (SLE), Systemic ... #rheumatology #diagnosis
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
lgE antibodies ... , and systemic lupus ... erythematosus ... #Classification ... #Diagnosis #Reactions
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Action: IgG/lgM antibodies ... , Haemolytic disease ... lupus erythematosus ... #types #allergy ... #table #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... lupus erythematosus ... #Systemic #Lupus ... #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... : - 10% SLE or ... lupus erythematosus ... #types #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
as systemic lupus ... , drug reactions ... vasculitis, and SLE ... #rheumatology # ... classification
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
affected joint • Systemic ... lupus erythematosus ... double-stranded DNA antibodies ... Tests for All Types ... #testing #Rheumatology
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