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rheumatology allergy hypersensitivity reactions vasculitis allergic cryoglobulinemia cryoglobulins differential erythematosus laboratory pathophysiology rheumatic rheumatoid table testing vasculitides workup
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Gravis, Graves' Disease ... Lupus Erythematosus ... , Reactive Arthritis ... #Classification ... #Diagnosis #Definitions
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
during hemolytic disease ... , and systemic lupus ... - Contact dermatitis ... #Classification ... Pathophysiology #Allergy #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... Differential Diagnosis ... • Type-I Interferonopathies ... #Systemic #Lupus
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • Autoimmune diseases ... : - 10% SLE or ... lupus erythematosus ... #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... inflammation Others: • Lupus ... as systemic lupus ... vasculitis, and SLE ... #rheumatology #classification
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
affected joint • Systemic ... lupus erythematosus ... (SLE) - Antinuclear ... Tests for All Types ... (to support a diagnosis
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