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differential classification allergy hypersensitivity types vasculitis antibodies comparison laboratory pathophysiology patterns pulmonary renal rheumatic rheumatoid seronegative sle syndrome systemic workup
Seronegative Inflammatory Arthritis - Differential Diagnosis • Seronegative Rheumatoid Arthritis • Infectious Arthritis: Viral, Bacterial,
: Systemic Lupus ... Erythematous, Systemic ... Vasculitis, Systemic ... Undifferentiated UCSD ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Juvenile Idiopathic Arthritis ... scleroderma), Rheumatoid Arthritis ... Juvenile Idiopathic Arthritis ... #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
arthritis, weight ... arthritis, adult-onset ... lung syndrome Arthritis ... Symptoms limited to: Arthritis ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... Glomerulonephritis, arthritis ... mucositis - Rash, arthritis ... , drug reactions ... #rheumatology #
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
erythematosus, ... Rheumatoid arthritis ... testing: anti-ANCA ... , anti-GBM ab, ANA ... #nephrology
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
, Haemolytic disease ... Examples: Rheumatoid arthritis ... glomerulonephritis, Systemic lupus ... erythematosus Type ... Examples: Contact dermatitis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
• Septic arthritis ... Arthritis: • ... when rheumatoid arthritis ... of reactive arthritis ... #testing #Rheumatology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
during hemolytic disease ... glomerulonephritis, rheumatoid arthritis ... , and systemic lupus ... erythematosus ... #Reactions #Table
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, drug reactions ... mucositis • Rash, arthritis ... often causes arthritis ... Glomerulonephritis, arthritis ... #Rheumatology
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