5 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Allergen-specific lgE antibodies ... glomerulonephritis, rheumatoid arthritis ... , and systemic lupus ... erythematosus ... - Contact dermatitis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... , inflammatory arthritis ... vasculitis, rheumatoid arthritis ... lung syndrome Arthritis ... Symptoms limited to: Arthritis
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Action: IgG/lgM antibodies ... to complement activation ... Examples: Rheumatoid arthritis ... glomerulonephritis, Systemic ... lupus erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and often causes arthritis ... Glomerulonephritis, arthritis ... mucositis - Rash, arthritis ... systemic lupus ... vasculitis, and SLE
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
SLE, atherosclerotic ... disease, drug reactions ... mucositis • Rash, arthritis ... and often causes arthritis ... Glomerulonephritis, arthritis