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diagnosis hematology oncology algorithm anemia aplastic apml causes chronic classification criticalcare differentiation encephalopathy foamed hematuria hemeonc hemophagocytic hlh hodgkins kidney
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis: Absolute blood ... Cytopenias: • Neutropenia ... microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease • Neutropenia ... factor (GCSF) treatments ... count with differential ... marrow studies Treatment ... #diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... hypertension and/or drug treatment ... , Kostmann syndrome ... including white blood ... cell aplasia DOI
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
(Goodpasture's syndrome ... Renal #Transplant #differential ... diagnosis #kidney #blood ... #urine #management ... #treatment #nephrology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Difficulty breathing • Neutropenia ... aplastic anemia Treatment ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... • Induce blast cell ... initiation • Differential ... APML #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Hypertensive emergency, Blood ... Reversible course Differential ... elevated white blood ... epilepticus Treatment ... #diagnosis #management
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
carry treatment ... for Refeeding Syndrome ... enough to prevent blood ... #diagnosis #differential ... #algorithm #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Workup: • Full Blood ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... with the HLH syndrome ... thrombocytopenia, neutropenia ... #Hematology #HemeOnc
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