928 results
Vitamin D Metabolism
Fat-soluble vitamin
Sources: dermal synthesis and food (dairy products, fish)
Active form: calcitriol (1,25-OH Vitamin D)
Main
vitamin Sources: dermal ... endocrinology #pathophysiology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... epidermis from dermis
Melanoma tumour progression (based on the Clark model)
 - Benign melanocytic nevi: controlled proliferation of normal
the papillary dermis ... vertically in the dermis ... #Pathophysiology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
deposit at the dermal-epidermal ... • Vasospasm of dermal ... Manifestations #pathophysiology
Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
karyorrhectic debris ... Dennis O'Malley
Strongyloides stercoralis Hyperinfection - Physical examination revealed reticulated purpuric patches with dusky centers on the abdomen,
bundles in the dermis ... #Clinical #Derm
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology
Blue nevus 
 - Dark blue-gray macule or papule 
 - Well-circumscribed 
 - Melanin localized
Melanin localized to dermis
Cellulitis and Skin Infections - Layers
 - Erysipelas (Epidermis)
 - Cellulitis (Dermis)
 - Necrotizing Fasciitis (Subcutaneous
- Cellulitis (Dermis
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... differ mainly in terms ... endocrinology #pathophysiology