Development criteria classification algorithm em dysfunction activation grading mas types

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Hypersensitivity: Definitions
• Type I - Production of lgE Abs that bind to harmless allergens and

allergens and activate mast ... degranulation, leading ... allergen causes development ... because T-Cell activation ... #Classification

Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of

Macrophage Activation ... IL-1 and IL-6, leading ... Presentation: • Rapid development ... nervous system (CNS) dysfunction ... Histopathologic criteria

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