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differential oncology common hypertension hypogammaglobulinemia immunodeficiency immunology leukemia management mds myelodysplasia myelodysplastic phtn platelet syndromes thrombocytosis variable workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... IgA, IgG, IgM (CVID ... changes), high MCV anemia ... ITP, unexplained pancytopenia ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... inflammatory disorders ... myeloid leukemia (CML ... #Causes #hematology
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... hemolytic anemia ... multifactorial mechanisms Hematologic ... #Diagnosis #Differential ... #Causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... , thrombocytopenia ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disorder with hypogammaglobulinemia ... infection risk secondary ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... Marrow Failure • Chronic ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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