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rheumatology algorithm champs complement cryofibrinogenemia cryoglobulins elevation erythematosus hypocomplementemia lactate lactic low lupus management mnemonic naildisorders sjogrens sle typea typeb
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
to Systemic Diseases ... #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm ... #causes
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulopathy, cirrhosis ... Chain deposition disease ... #differential # ... hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... • Autoimmune diseases ... - type II cryoglobulinemia ... Secondary to Autoimmune ... #types #classification
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
• Secondary form ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... primary biliary cirrhosis ... renal tubular acidosis
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Divided Into Two Types ... processes: • Systemic ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
presentations and disease ... of Circulatory System ... - Compartment syndrome ... #Diagnosis #causes ... classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... • Type-I Interferonopathies ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation
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