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rheumatology systemic algorithm generalized oncology agglutinin cryofibrinogenemia cryoglobulinemia cryoglobulins dermatologic gpa granulomatosis hemolytic hodgkins lupus lymphoma management mds myelodysplasia myelodysplastic
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Differential Diagnosis ... Myelodisplastic syndrome ... #primary #secondary ... #generalized #dermatology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Iron deficiency anemia ... • Nephrotic syndrome ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
renal failure/uremia ... Myelodisplastic syndrome ... #secondary #systemic ... #generalized #dermatology ... #causes
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Disease 3 Types ... Syndrome (CAS): ... Viral Infection Clinical ... anemia • Cold ... #hematology #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... associated with pruritus ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Divided Into Two Types ... • Painful or pruritic ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • Autoimmune diseases ... Secondary to Autoimmune ... systemic lupus erythematosus ... #types #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... • Type-I Interferonopathies ... lymphopenia, low PLT • Anemia ... #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... • Pruritis ... Immunohistochemical studies (to differentiate ... number of sites of disease ... #hematology #oncology
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