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dermatology vasculitis agglutinin cold cryofibrinogenemia cryoglobulinemia dermatologic globulin granulomatosis hemolytic lupus nonpalpable palpable polyangiitis protein proteingap purpura rash sle systemic
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... associated vasculitis - GPA ... #diagnosis #types ... #classification ... #rheumatology #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... vasculitis - GPA ... #Diagnosis #hematology ... #rheumatology #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA ... polyangiitis (GPA ... GPA causes disease ... #Polyangiitis #GPA ... #diagnosis #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Divided Into Two Types ... • Painful or pruritic ... • Negative causes ... #rheumatology # ... hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
> PR3 60% • GPA ... tract, and often causes ... • ANCA (Dx: GPA ... #diagnosis #rheumatology ... #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... • Type-I Interferonopathies ... lymphopenia, low PLT • Anemia ... #Diagnosis #Rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
3 Types of Cold ... Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... #hematology #diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Globulin - Protein Gap ... changes (POEMS syndrome ... gastric tumors • Hematology ... Comment on type ... #diagnosis #hematology
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