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rheumatology syndrome lupus summary table differential disease druginduced erythematosus neurology systemic thrombocytopenia activation aecopd algorithm antinxp2 antinxp2dm apml arthritis associations
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
rheumatoid arthritis SLE ... ConnectiveTissueDiseases #ILD ... LungDisease #CTILD #Diagnosis ... #Differential #Comparison ... #Table #Pulmonary
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
, holster sign, ... Classic triad of ILD ... Can also see mechanics ... after 2 years of treatment ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
severe disease Treatment ... : • Mild disease ... #Summary #diagnosis ... #rheumatology # ... management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Prognosis: Usually mild ... Usual therapeutic management ... #comparison #table ... #rheumatology # ... diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Disease, PRES Pathophysiology ... permeability Diagnosis ... Erythematosus #SLE ... #management #treatment
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
: 33% • Treatment ... , and CXR with pulmonary ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... cytokines (TNFa,lL1, IL6 ... Autoimmune diseases: SLE ... Unknown cause Treatment ... #management #treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD) Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... limitation (GOLD Ill ... Lung US, Echo, LE ... #Exacerbation #treatment ... #pulmonary
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... #management #hematology
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