28 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... microangiopathies (TMA) - TTP ... syndrome (ST-HUS ... organ or stem cell ... #hematology #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... thrombocytopenic purpura (TTP ... syndrome (HUS) ... lymphoproliferative disorders ... #hematology #anemia
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... TTP/HUS indicates ... uremic syndrome ... thrombocytopenia, Hematology ... 2012, p 193 #Diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... disease - DIC/TTP ... /HUS - Hemolytic ... #hematology #rheumatology ... #nonpalpable #dermatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Pregnancy - TTP ... the critically ill ... defects. 1) HELLP (Hemolysis ... AFLP #obstetrics #hematology ... #diagnosis #table
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... thrombocytopenia - DIC, TTP ... Consider RBC membrane disorder ... #Algorithm #workup ... #hematology #testing
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... lymphoproliferative disorders ... microglobulin Treatment ... #workup #oncology ... #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Fragmentation - MAHA: TTP ... Drug-associated, PCH, Evans Syndrome ... #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... defects. 1) HELLP (Hemolysis ... of child 3) TTP ... Obstetrics #OBGyn #Hematology ... #Table
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
iron deficiency, hemolysis ... Chronic inflammatory disorders ... Myelodysplastic syndrome ... myeloid leukemia (CML ... #Causes #hematology