5 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Cell Disease Vaso-occlusive ... Osteomyelitis / Septic Arthritis ... • Differentiate ... #Disease #differential ... diagnosis #causes #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Ligament • Bone ... the subchondral bone ... #MSK #rheumatology ... #approach #workup ... #differential #
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hemolytic anemia • Pain ... Workup: • Full ... Immunohistochemical studies (to differentiate ... anymore • Routine bone ... : • Based on number
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Send for cell count ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
presents with pain ... thoracic more than lumbar ... • Non-Hodgkin Lymphoma ... Oncology #Diagnosis #Workup ... #Hematology