9 results
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... Spine” Fusion of Lumbar ... Erythematosus (SLE ... Joint #Disorders #msk ... #Differential #
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... calcium-b) • Laboratory ... 40, F:M 9:1 • Clinical ... #table #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... and fever) and laboratory ... permanent alopecia Differential ... Malignancy (e.g. hematologic
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Juvenile Idiopathic Arthritis ... Juvenile Idiopathic Arthritis ... ANA #patterns #rheumatology ... #diagnosis #differential
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
spondyloarthropathies, lupus ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... more time for the laboratory ... titer, ACE level, CXR ... ANA and RF (if clinical ... #laboratory #workup
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... pathognomonic laboratory ... Behcet disease) Differential ... Oral aphthae : SLE ... : SLE, Reactive
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
syndrome, rheumatoid arthritis ... , SLE Myasthenia ... Clinical Picture ... life-threatening Differential ... immunologic assay - MuSK
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... is rare in DIL, SCLE-DIL ... calcium-b) • Laboratory ... #DIL #rheumatology