28 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... Diagnosis via genetic ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
• Specific for SLE ... Treatment: • ... #Summary #diagnosis ... #rheumatology # ... management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... brain injury By Association ... Anesthesiology #Anesthesia ... #Checklist #Diagnosis ... #Management #Workup
Can’t Intubate, Can’t Oxygenate (CICO) - Guidelines for Crises in Anaesthesia
This is the last resort when
Access – FoNA (see ... By Association of ... Anesthesiology #Anesthesia ... Intraoperative #Checklist ... #Diagnosis #Management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... life-threatening • Treatment ... : Chronic disease ... Erythematosus #Diagnosis ... #rheumatology
Intraoperative Bronchospasm - Guidelines for Crises in Anaesthesia

❶ Call for help and inform theatre team of
suspected airway see ... Consider alternate diagnoses ... Anesthesiology #Anesthesia ... Intraoperative #Checklist ... #Diagnosis #Management
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
❹ Call for MH treatment ... COMPLICATIONS AND OUTLINE TREATMENTS ... platelets By Association ... Intraoperative #Checklist ... #Diagnosis #Management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • ... Oral aphthae : SLE ... Arthritis, AS Treatment ... #management #signs ... #symptoms #rheumatology
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia
Hypertension is most commonly due to inappropriate depth of
alfentanil can be diagnostic ... – see Box C for ... Anesthesiology #Anesthesia ... Intraoperative #Checklist ... #Diagnosis #Management