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diagnosis hematology disease management workup activation agglutinin algorithm amyloidosis ana antinuclear autoantibodies autoinflammatory behcet cancer chronic classification cll cold dementia
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... Amyloidosis Clinical ... : • Nephrotic syndrome ... protein-albumin" dissociation ... Carpal tunnel syndrome
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... Abnormalities: macrocytic anemia ... peripheral blood myeloid ... Autoinflammatory #Somatic #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Asia • HLA-B51 association ... • M > F Clinical ... (Clinical Dx). ... is a skin prick test ... signs #symptoms #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
-15% If SLE is clinically ... suspected, tests ... SLE-SSc-AlM overlap syndromes ... Negative association ... erythematosus #diagnosis #rheumatology
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
workup 1) Clinical ... ... laboratory tests ... - Progressive amnesia ... Aphaso-apraxo-agnosia syndrome ... ischemic stroke - Amyloid
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... with leukopenia, anemia ... Liver function tests ... #Rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... • Diagnostic Test ... Donath-Landsteiner test ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Orange or Hep C Clinical ... • Neutropenia, anemia ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... Myelodysplastic syndromes ... evolution to acute myeloid ... disease tolerate anemia ... importance of clinical
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