9 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
common sites: hip ... , shoulder ... Osteomyelitis / Septic Arthritis ... #differential #diagnosis ... #causes #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... should be obtained ... : HIV test, a rubella ... (to support a diagnosis ... #testing #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... axial (spine, shoulders ... , hips)? ... weeks) Can Be Caused ... #MSK #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
, and back and shoulders ... -74%] • Blood tests ... • Arthralgia/arthritis ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... What we should be ... / hypoxemia -> focus ... tests before beginning ... Ethylene glycol - HIV
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... proximal muscles of shoulder ... and hip • Muscle ... tract, and often causes ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... retinopathy Lab Tests ... Cryoglobulins • HIV ... #rheumatology #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
gap (>4 g/dL) should ... infections (acute HIV ... (RA, Temporal arteritis ... #differential #diagnosis ... #hematology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tests: • Measure ... RP-ILD), dermato-rheumatologic ... weakness + atrophy- Hip ... • Nonerosive arthritis ... statins - probably caused