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differential classification disease hematology joint pain vasculitis acidosis antimda5dm autoimmune bone dermatology dermatomyositis elevation gap globulin laboratory lactate lactic monoarthritis
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
, and back and shoulders ... -74%] • Blood tests ... • Arthralgia/arthritis ... #rheumatology # ... dermatology #diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
common sites: hip ... , shoulder ... Osteomyelitis / Septic Arthritis ... #differential #diagnosis ... #causes #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... should be obtained ... : HIV test, a rubella ... (to support a diagnosis ... #testing #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... axial (spine, shoulders ... , hips)? ... weeks) Can Be Caused ... #MSK #rheumatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... What we should be ... / hypoxemia -> focus ... tests before beginning ... Ethylene glycol - HIV
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... proximal muscles of shoulder ... and hip • Muscle ... tract, and often causes ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... retinopathy Lab Tests ... Cryoglobulins • HIV ... #rheumatology #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gap (>4 g/dL) should ... infections (acute HIV ... (RA, Temporal arteritis ... #differential #diagnosis ... #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tests: • Measure ... RP-ILD), dermato-rheumatologic ... weakness + atrophy- Hip ... • Nonerosive arthritis ... statins - probably caused
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