12 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
common sites: hip ... , shoulder ... Osteomyelitis / Septic Arthritis ... #diagnosis #causes ... #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
present both at rest ... e.g., congenital hip ... Joint #Pain #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Asia • HLA-B51 association ... Positive pathergy test ... is a skin prick test ... Behcet disease) Differential ... signs #symptoms #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... should be obtained ... : HIV test, a rubella ... (to support a diagnosis ... #testing #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... axial (spine, shoulders ... , hips)? ... #Diagnosis #MSK ... #rheumatology #
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
, and back and shoulders ... -74%] • Blood tests ... • Arthralgia/arthritis ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
, and hip muscle ... and hips ... for giant cell arteritis ... normal and can help differentiate ... #Management #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Diagnosis Framework ... retinopathy Lab Tests ... Cryoglobulins • HIV ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... proximal muscles of shoulder ... and hip • Muscle ... #Diagnosis #Rheumatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... Diagnosis The ... / hypoxemia -> focus ... tests before beginning ... Ethylene glycol - HIV