14 results
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Alkalosis - Differential ... hyperaldosteronism • High PRA: Renal ... Diagnosis #Algorithm #Nephrology ... #Causes
Distal Renal Tubular Acidosis (RTA)  Type 1 

Totally scuppers the kidney's acidification mechanism. Will be
Distal Renal Tubular ... diagnosis with direct urine ... Failure to acidify urine ... #Diagnosis #Management ... #Nephrology #Causes
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
A urine K/Cr ratio ... suggests extra-renal ... Alkalosis: Emesis ... Proximal RTA, Distal ... differential #potassium #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... diuretics after renal ... generally indicates a renal ... #Diagnosis #Causes ... #nephrology
Blood gas analysis
Metabolic alkalosis
Measured urine CI
< 10 mEq/L
Saline responsive
> 10 mEg/L
Not saline responsive
- Vomiting or NG
gas analysis Metabolic ... alkalosis Measured ... urine CI < 10 ... of H+ loss Renal ... mineralocorticoid excess - Distant
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Alkalosis - Differential ... hyperaldosteronism • High PRA: Renal ... Diagnosis #Algorithm #Nephrology ... #Causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Summary Causes ... Heat stroke - Metabolic ... Weakness - Dark urine ... #nephrology
Metabolic Causes of Kidney Stones in Children
 • Calcium Oxalate: Primary Hyperoxaluria type 1-3, Secondary Hyperoxaluria
Metabolic Causes ... Calcium Phosphate: Distal ... #Causes #Kidney ... #Stones #pediatrics ... #nephrology #differential
Methotrexate Renal Toxicity 
Prevention:
 • Alkalinize the urine, keep urine ph >7
 • Start pre-treatment 12
Methotrexate Renal ... fluids till you see metabolic ... alkalosis • Forced ... #Toxicity #management ... #treatment #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
of cells on the distal ... alkalosis • Normal ... (spot urine, calcium-creatinine ... Syndrome #diagnosis #nephrology ... #management #pathophysiology