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diagnosis treatment rheumatology lupus signs symptoms cardiology checklist differential erythematosus hematology neurology summary systemic aflp anesthesia anesthesiology bundle cardiomyopathy cerebritis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... Myopathy (Also caused ... Erythematosus #SLE ... Musculoskeletal #Complications ... #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... cerebritis #diagnosis #management
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... Phenomenon #Lupus #SLE ... Manifestations #pathophysiology ... signs #symptoms #complications
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... Monitor and Treat Complications ... obgyn #diagnosis #management ... #pathophysiology
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia Unexplained increase in ETCO2 AND tachycardia AND increased
Guidelines for Crises ... other, more common causes ... Box C). ⓬ Treat complications ... as indicated COMPLICATIONS ... Checklist #Diagnosis #Management
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
(idiopathic), CNS ... Incr PVR if a complication ... SUI or UUI not caused ... Incontinence #Mixed #Pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Diagnosis and Management ... Dermatomyositis) AKI - Pathophysiology ... levels > 8mg/dL See ... Differential #Diagnosis #Management ... #Summary #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... leukostasis syndrome: CNS ... lymphocytic lymphoma (SLL ... Transformation: • Complication
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... 100 mg/m2) : in case ... Lymphohistiocytosis #diagnosis #management
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