21 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... hypothalamus =>Prader-Willi ... Syndrome Signs ... #PraderWilli #Syndrome ... pathophysiology #peds #pediatrics
Hoffman's sign. Even in this specific case, accompanied by a clonus outline (rhythmic contractions). The median
Hoffman's sign. ... middle finger. 2) Ask ... #Hoffmanns #Sign ... #Reflex #Positive ... Abnormal #clinical #video
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... an involuntary reflex ... Video by Dr. ... Meningitis #Clinical #Video ... #PhysicalExam #Pediatrics
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... bladder and rectal reflex ... pathophysiology #signs ... #symptoms #msk
Freiberg's Test for Piriformis Syndrome

Flex the hip to 90 degrees, internally rotate the hip.
Pain in the
for Piriformis Syndrome ... Flex the hip ... #Piriformis #syndrome ... lumbar #clinical #video ... #physicalexam #msk
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... lumbar spine Signs ... of normal leg reflexes ... #CaudaEquina #Syndrome ... #MSK #pathophysiology
Positive Hoffmann's sign (finger flexor reflex)

Flexion and adduction of the thumb and flexion of the index
Positive Hoffmann's sign ... (finger flexor reflex ... #Hoffmanns #sign ... clinical #hand #video ... #physicalexam #msk
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... seizure, primitive reflexes ... pathophysiology #geriatrics ... #diagnosis #signs
Newborn Infant - Routine Examination

Birthweight, gestational age and birthweight percentile are noted.
General observation Of the baby's
is also a late sign ... checked for red reflex ... This reflex is not ... are observed for signs ... Examination #Peds #Pediatrics
Primitive Suck, Rooting Reflex on Newborn Physical Exam 
The normal response to stroking the lateral aspect
Suck, Rooting Reflex ... toes or “Babinski sign ... Rooting #Primitive #Reflex ... PhysicalExam #clinical #video ... #peds #pediatrics