22 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Osmotic diuretics (e.g ... Loop diuretic (e.g ... Thiazides-type diuretics (e.g ... nephron #diuretics #pharmacology ... #nephrology #medications
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... ) Loop agents (eg ... Adenosine #Nephron #Pathophysiology ... Sites #Action #nephrology ... #pharmacology
Algorithm showing a stepwise approach to the assessment and investigation of a possible neuropathy. CIDP, chronic
Charcot-Marie-Tooth; EMG ... GBS, Guillain-Barré ... #Diagnosis #Neurology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Hypothyroidism • Medication-induced ... CIDP, Guillain-Barre ... #differential #diagnosis ... #causes #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Pathophysiology ... Diagnosis: • ... Electrodiagnostic studies - EMG ... #Syndrome #diagnosis ... management #treatment #neurology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
polyneuropathy (e.g ... Guillain-Barré syndrome ... #differential #diagnosis ... #table #neurology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC ... #differential #diagnosis ... #pathophysiology ... #pharmacology # ... potassium #medications
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology ... GBS #Guillain #Barre ... #management #neurology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
- Differential Diagnosis ... Tuberculosis • Epstein-Barr ... Pulmonary Disease Neurologic ... Myasthenia Gravis Pharmacologic ... • Drug Abuse (e.g
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Pathogenesis and Medications ... -5 inhibitors (e.g ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology ... #Urology