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diagnosis management rheumatology differential neurology syndrome amyloid amyloidosis arthritis chronic classification cryoglobulinemia cryoglobulins daytime dermatology dili disease druginduced eosinophil eosinophilia
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm Insufficient Sleep • Poor Sleep Hygiene • Insomnia
Shift Work) Sleep ... (Eg. ... • Medications (Eg ... • Drug Abuse (Eg ... Excessive #Daytime #Fatigue
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... • Rheumatoid Arthritis ... • Drug Abuse (e.g ... • Somatization Disorder
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... evaluation or workup ... signs or symptoms (eg ... #diagnosis #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
of information (e.g ... for alternative causes ... Hepatic vascular disorder ... (e.g. ascites), ... #hepatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... arthralgia, and arthritis ... (e.g. systemic
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... not be subtle e.g ... . extreme fatigue ... E.g. 80 yo ESR cutoff ... vision changes, etc
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... evidence of (fatigue ... • Malignancy (e.g ... . hematologic) ... (e.g. thyroid disease
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... nonerosive inflammatory arthritis ... Rule out other causes ... antiinflammatory properties e.g ... Tetracyclines etc
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... inflammatory disease (e.g ... Chemistry profile (e.g ... metabolic or endocrine disorders ... ANA and RF (if clinical
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
an autoimmune disorder ... syndrome, rheumatoid arthritis ... Clinical Picture ... - Generalized fatigue ... Serologic and EMG
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