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diagnosis management rheumatology syndrome algorithm differential erythematosus hepatology sle systemic acidosis activation antinxp2 antinxp2dm arteritis blood cerebritis cns cryoglobulinemia cryoglobulins
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... glucocorticoid treatment ... signs or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
toxic aetiology: Skin ... of information (e.g ... non-essential drug/HDS treatments ... for alternative causes ... vascular disorder (e.g
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Disease Classification ... • Malignancy (e.g ... Endocrine disorders (e.g
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... and lower jaw Treatment ... antiinflammatory properties e.g ... Tetracyclines etc ... diagnosis #management #Dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
underlying disease (eg ... SJIA], systemic lupus ... • Infection (eg ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Syndrome: • Clinical ... tissue disorder (e.g ... . systemic lupus ... diagnosis #types #classification
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... hypoxemia/Sepsis etc ... before beginning treatment ... #typea #typeb #classification
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... required due to skip
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Clinical Manifestations ... unit activity on EMG ... of diazepam • EMG ... EMG Studies: ... #neurology
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