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diagnosis management differential neurology treatment algorithm workup disease anemia cardiology oncology vasculitis classification dermatology disorders erythematosus lupus physicalexam sle systemic
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... unless worrisome EKG ... diagnosis #management #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... for secondary causes ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Raynaud's Syndrome - Washing off under hot water. Raynaud phenomenon is an exaggerated vasoconstrictive response of the
Raynaud's Syndrome ... and arterioles (e.g ... #Raynauds #Syndrome ... disease #phenomenon #clinical ... fingers #hands #rheumatology
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 Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... Differential #Diagnosis #Causes ... #hematology #secondary
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... lumbar spine Signs ... #MSK #pathophysiology ... #signs
Raynaud's Syndrome - Washing off under hot water wath. Raynaud phenomenon is an exaggerated vasoconstrictive response of
Raynaud's Syndrome ... and arterioles (e.g ... #Raynauds #Syndrome ... disease #phenomenon #clinical ... fingers #hands #rheumatology
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 Problem Representation - Approach to the Infectious Disease Patient Who: Patient age and host/risk factors (such as
illness What: Key signs ... and symptoms that ... define the clinical ... syndrome - Does ... illness script (e.g
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Iron Deficiency (Eg ... Other • e.g ... HgbE, HgbC, etc. ... #Hematology
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