16 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... for secondary causes ... glucocorticoid treatment ... organ-specific signs ... or symptoms (eg
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Pathophysiology ... meningococcal, H1N1) Clinical ... Clinical Features ... Electrodiagnostic studies - EMG
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... unless worrisome EKG
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... than one after symptom ... Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology ... and cauda equina TREATMENT
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... Treatment of GCA
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... to produce all classes ... /Symptoms/Findings ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... renal failure Clinical ... are not caused ... of diagnosis (e.g ... Diagnosis #Management #Signs
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... fasciculations Common Symptoms ... EMG: LMN Signs in ... diagnosis column Treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... hypoxemia/Sepsis etc ... / hypoxemia -> focus ... before beginning treatment
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Person Syndrome Pathophysiology ... Clinical Manifestations ... unit activity on EMG ... of diazepam • EMG ... EMG Studies: