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diagnosis management neurology differential syndrome hematology treatment agammaglobulinemia alkpos amyotrophic anaplastic anemia barre bcnie bloodculture disorders endocarditis eosinophil eosinophilia gbs
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... /µL Workup • Screen ... neoplasms) • Screen also ... (eg, skin or esophageal
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... unless worrisome EKG
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... Inability to produce all ... immunity Signs/Symptoms ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the clinical ... lateral sclerosis Pathophysiology ... - Causes progressive ... fasciculations Common Symptoms ... EMG: LMN Signs in
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Bell's Palsy - Diagnosis ... - Atypical Clinical ... Imaging (if atypical symptoms ... CNS inflammatory cause ... ) • EMG/NCS (rare
Anaplastic large cell lymphoma, ALK+ Clinical • First 3 decades of life, M>F • Often nodal +
cell lymphoma, ALK ... + Clinical • ... advanced stage + B symptoms ... sometimes fried-egg ... than one • Rare cases
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... renal failure Clinical ... are not caused ... mediators such as ... of diagnosis (e.g
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
antimicrobials, clinical ... but important causes ... special stains (e.g ... specific pathogens also ... #infectiousdiseases
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Clinical Manifestations ... unit activity on EMG ... of diazepam • EMG ... antibody that works ... EMG Studies:
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Incidence: 1 to 2 cases ... transplantation CLINICAL ... than one after symptom ... Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology
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