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diagnosis management clubbing syndrome ucsdh activation antimda5 antimda5dm antinxp2 antinxp2dm autoimmune differential erythematosus gca giantcell hematology lupus macrophage mas myopathy
Terry's Nails Proximal paleness extending halfway up the nail, often eliminating the lunula. Darker distal band. Seen
states of stress (e.g ... #Terrys #Fingernails ... #PhysicalExam #Clinical ... #Photo #Sign
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... auricular papules Clinical ... • Arthralgia/arthritis ... #rheumatology # ... dermatology #diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... them, but urgent rheumatology
Clubbing of the Fiingers: Bulbous appearance of the distal fingers associated with a number of uncommon
lung conditions (e.g ... , IPF, cancer, etc ... Images #Clinical ... #Photo #Clubbing ... #Fingernails #UCSDH
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Fever is the main clinical ... underlying disease (eg ... • Infection (eg ... Diagnosis #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Still disease, dermatomyositis ... Non-autoimmune rheumatologic ... • Malignancy (e.g ... Endocrine disorders (e.g
Clubbing of the Fiingers: Bulbous appearance of the distal fingers associated with a number of uncommon
lung conditions (e.g ... IPF, cancer, etc ... Images #Clinical ... #Photo #Clubbing ... #Fingernails #SchamrothsSign
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... antiinflammatory properties e.g ... Tetracyclines etc ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... auricular papules Clinical ... Prednisone at 1 mg/kg ... diagnosis #management #rheumatology ... #dermatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... • Nonerosive arthritis
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