12 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... WBC >100k, + lab signs ... : • Pathophysiology ... unless worrisome EKG
Problem Representation - Approach to the Infectious Disease Patient

Who: Patient age and host/risk factors (such as
, splenectomy, etc ... illness What: Key signs ... and symptoms that ... define the clinical ... syndrome - Does
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... any time during treatment ... polymyositis, dermatomyositis ... IU/I • SAMS clinical ... (SAMS-CI) • EMG
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... patients with clinically ... stimulation Clinical ... Multiple Sclerosis Treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Herpes, Coxsackie, etc ... : Polymyositis/Dermatomyositis ... Clinical Features ... : • Triad of symptoms ... urine • Other symptoms
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Pathophysiology ... Clinical Manifestations ... autoantibodies - TPO, TTG, etc ... Treatment: • ... Diagnosis #Management #treatment
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... renal failure Clinical ... of diagnosis (e.g ... Diagnosis #Management #Signs ... #Symptoms
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... • EEG: With persistent ... epilepticus Treatment ... underlying cause • Treatment
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... vision changes, etc ... Treatment of GCA ... GCA #Temporal #Signs
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... lateral sclerosis Pathophysiology ... fasciculations Common Symptoms ... EMG: LMN Signs in ... diagnosis column Treatment