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diagnosis differential hematology elevatedmcv macrocytosis management microcytic b12 chronic cobalamin daytime deficiency excessive mds myelodysplasia myelodysplastic neurology nutrition oncology person
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... 95 (or 100) is macrocytic ... (BM) ablative disorders ... of substrate (e.g ... #Workup #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Drugs Oval Macrocytes ... Increased Requirement (e.g ... • Small Bowel Disorder ... #Causes #Hematology
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm Insufficient Sleep • Poor Sleep Hygiene • Insomnia
Causes of Excessive ... Differential Diagnosis Algorithm ... Shift Work) Sleep ... Excessive #Daytime #Fatigue ... #Causes
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Hematologic • Anemia ... • Drug Abuse (e.g ... • Somatization Disorder ... #causes
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Differential Diagnosis Algorithm ... HgbE, HgbC, etc. ... #Microcytic #Anemia ... Differential #Diagnosis #Algorithm
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... dysfunction, and/or disorders ... : • Worsening macrocytic ... anemia, yellow ... slowing, neuropathy, fatigue
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Symptoms: • Fatigue ... common cytopenia: Macrocytic ... Workup: • Complete
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... and pernicious anemia ... other neurological disorders ... antibody that works ... limb or joint disorders
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