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rheumatology management differential signs sle erythematosus systemic druginduced syndrome activation ana antibodies antinuclear approach autoantibodies causes cell checklist classification comparison
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of hip (rare), Arthritis ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
• Inflammatory arthritis ... Noninflammatory arthritis ... with rheumatoid arthritis ... oxalate Infectious Arthritis ... #arthritis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Diagnosis Manifestations ... : - Arthritis ... - Hemolytic anemia ... autoantibodies #signs #symptoms ... #differential #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... , Arthritis, myalgia ... sle #comparison #table ... diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, inflammatory arthritis ... vasculitis, rheumatoid arthritis ... lung syndrome Arthritis ... : • Symptoms limited ... to: Arthritis,
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... Juvenile Idiopathic Arthritis ... scleroderma), Rheumatoid Arthritis ... Juvenile Idiopathic Arthritis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... ) Giant cell arteritis ... Diagnosis = clinical ... versus Temporal Arteritis ... #GiantCell #arteritis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... juvenile idiopathic arthritis ... with leukopenia, anemia ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... l MD SOAP) - Risks ... pylori test (GI symptoms ... changes), high MCV anemia
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Diseases • Septic arthritis ... of Inflammatory Arthritis ... when rheumatoid arthritis ... of reactive arthritis
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