ECG qtc table diagnosis syndrome algorithm comparison neurology hematology anemia macrocytic

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Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
• Thalassemia

Algorithmic Approach ... Diagnosis Framework ... aciduria, Drugs (e.g ... #MCV #Algorithm ... #hematology

Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95

Anemia Diagnostic ... 95 (or 100) is macrocytic ... of substrate (e.g ... #Algorithm #Diagnosis ... #Workup #Hematology

Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
•

- Differential Diagnosis ... Algorithm Normal ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Hematology

Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
- Decreased/NormaI

- Differential Diagnosis ... Algorithm Decreased ... • Secondary (e.g ... #Algorithm #Causes ... #Hematology

Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),

RBC) Morphology Microcytic ... (sometimes) Macrocytic ... Chemotherapy (e.g ... #differential #diagnosis ... #hematology #microscopy

Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or

- Differential Diagnosis ... Algorithm Decreased ... HgbE, HgbC, etc. ... #Microcytic #Anemia ... #Hematology

Causes of Thrombocytopenia - Differential Diagnosis Algorithm

Decreased Megakaryopoiesis
• Aplastic Anemia
• Toxic Damage (e.g.

- Differential Diagnosis ... Algorithm Decreased ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... #Hematology

Blood Disorders - Markers and Differential Diagnosis Algorithm
Acute
• Myloid (AML) - CD13, CD33, CD34,

Algorithm Acute ... Pseudo Pelger-Huet, Macrocytic ... anemia - ... Blood #Disorders #hematology ... #Algorithm

Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
• Hypo/Hyperthyroidism
• Diabetes
• Pituitary Insufficiency
• Adrenal

Neoplastic / Hematologic ... • Anemia • ... Pulmonary Disease Neurologic ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome

Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
• SLE
• Scleroderma
• Dermatomyositis
Koilonychia - Spoon-shaped

Iron deficiency anemia ... halt nail growth (e.g ... • Nephrotic syndrome ... #Differential #Diagnosis ... #Algorithm #causes

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