11 results
Comparison - Serotonin Syndrome, Neuroleptic Malignant Syndrome, and Malignant Catatonia

- BWH Medicine Chiefs @BrighamChiefs

#Serotonin #Syndrome #Neuroleptic
Comparison - Serotonin ... Malignant Syndrome ... #NMS #SS #comparison ... #diagnosis #management ... #treatment #table
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... chemosensitive malignancy ... with Ca only if EKG ... Walid Malki, MD, MS ... TLS #oncology #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... organ damage • Treatment ... Low calcium • Treatment ... unless worrisome EKG ... TLS #diagnosis #management
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
TNF-a1pha, IL-6, etc ... syndrome; Serotonin ... syndromeTreatment ... #Hyperthermia #comparison ... #diagnosis #management
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... iniury, Compartment syndrome ... syndrome Nontraumatic ... Herpes, Coxsackie etc ... per day until stable
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Cardiac, pulmonary etc ... • Acute stroke syndromes ... system: Brain tumor ... • Neoplastic: Malignancy-associated ... electromyographic (EMG
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
Torsades de Pointes - Management ... Algorithm Drugs ... Syndrome Electrolyte ... Hypocalcemia (rarely) Treatment ... #Algorithm
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... - Seizures - Malignant ... - Neuroleptic malignant ... Herpes, Coxsackie, etc ... per day until stable
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... : • Tumor-like ... Multiple Sclerosis Treatment ... sclerosis #diagnosis #management ... #neurology #treatment
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
as infectious, malignant ... and lower jaw Treatment ... antiinflammatory properties e.g ... Tetracyclines etc ... Rheumatology #diagnosis #management